Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816136 | 0.85 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4820005 | 0.85 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6255056 | 0.85 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4824452 | 0.85 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4819570 | 0.85 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4819578 | 0.83 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL9003269 | 0.83 | MAPT (0.70) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4825310 | 0.82 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6250721 | 0.80 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4825305 | 0.80 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358438-A2 | Ethanesulfonamide derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4874771-A | ANTISECRETORY, ANTIULCER AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |