Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341645 | 0.85 | MAPT (0.60) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4824452 | 0.83 | MAPT (0.63) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL6255056 | 0.83 | MAPT (0.59) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4820005 | 0.83 | MAPT (0.59) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4819570 | 0.83 | MAPT (0.59) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4819578 | 0.82 | MAPT (0.57) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL9003269 | 0.82 | MAPT (0.70) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4825310 | 0.81 | MAPT (0.64) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL7063836 | 0.79 | MAPT (0.61) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL6250721 | 0.78 | MAPT (0.57) | MAPTMEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7347879-B2 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'Oreál, S.A. (FR) | 2008-03-25 | — | — | US | disclosed |
| US-7347879-B2 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'Oreál, S.A. (FR) | 2008-03-25 | — | — | US | disclosed |
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | KRT18, CDC73, DSG1 | MAPT 2238/4885MEN1 3813/4885KMT2A 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.