Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PTPRF | P10586 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153567 | 0.94 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL4951837 | 0.91 | ALDH1A1 (0.73) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL18549022 | 0.90 | ALDH1A1 (0.66) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL14117517 | 0.90 | ALDH1A1 (0.66) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL6851290 | 0.89 | ALDH1A1 (0.60) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL11194633 | 0.88 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL4817738 | 0.88 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL10489391 | 0.88 | MAPT (0.72) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL5355772 | 0.88 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2AGLA | |
| SCHEMBL1024700 | 0.88 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835587-A | Synthesis method of diamine compound and diamine compound prepared by synthesis method | 合肥中聚和成电子材料有限公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20190256471-A1 | SMALL MOLECULE INHIBITORS OF BOTULINUM NEUROTOXINS | THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AR (US) | 2019-08-22 | — | — | US | disclosed |
| US-10301265-B2 | Small molecule inhibitors of botulinum neurotoxins | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2019-05-28 | — | — | US | disclosed |
| US-10011704-B2 | Rubber composition, tire, bisphenyldiamine compound, and anti-aging agent | OTSUKA CHEMICAL CO., LTD. (JP) | 2018-07-03 | — | — | US | disclosed |
| EP-3147319-B1 | RUBBER COMPOSITION, TIRE, BISPHENYL DIAMINE COMPOUND AND ANTI-AGING AGENT | OTSUKA CHEMICAL CO LTD (JP) | 2018-06-13 | — | — | EP | disclosed |
| US-20170137604-A1 | RUBBER COMPOSITION, TIRE, BISPHENYLDIAMINE COMPOUND, AND ANTI-AGING AGENT | OTSUKA CHEMICAL CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
| EP-3147319-A1 | RUBBER COMPOSITION, TIRE, BISPHENYL DIAMINE COMPOUND AND ANTI-AGING AGENT | Otsuka Chemical Co., Ltd. (JP) | 2017-03-29 | — | — | EP | disclosed |
| US-20110294848-A1 | SMALL MOLECULE INHIBITORS OF BOTULINUM NEUROTOXINS | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2011-12-01 | — | — | US | disclosed |
| US-20110294848-A1 | SMALL MOLECULE INHIBITORS OF BOTULINUM NEUROTOXINS | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2011-12-01 | — | — | US | disclosed |
| EP-0487019-B1 | Use of a nonlinear optical compound | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1996-09-25 | — | — | EP | disclosed |
| EP-0384364-B1 | A composition of nonlinear optical materials and a method for preparing the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5154858-A | Mixture of 2-(p-chlorophenyl)imidazoline and a compound having an electron donative and an electron attractive group | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0487019-A2 | Use of a nonlinear optical compound | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-5009815-A | Composition of nonlinear optical materials and a method for preparing the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| EP-0384364-A2 | A composition of nonlinear optical materials and a method for preparing the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301265-B2 | Small molecule inhibitors of botulinum neurotoxins | RAC2, BTN3A1, GDI1 | MAPT 2064/4885ALDH1A1 4398/4885MEN1 2424/4885 |
| US-20190256471-A1 | SMALL MOLECULE INHIBITORS OF BOTULINUM NEUROTOXINS | RAC2, BTN3A1, GDI1 | MAPT 2064/4885ALDH1A1 4398/4885MEN1 2424/4885 |
| US-10011704-B2 | Rubber composition, tire, bisphenyldiamine compound, and anti-aging agent | RRS1, POT1, RAD54L | MAPT 2363/4885ALDH1A1 2196/4885MEN1 2712/4885 |
| US-20170137604-A1 | RUBBER COMPOSITION, TIRE, BISPHENYLDIAMINE COMPOUND, AND ANTI-AGING AGENT | RRS1, POT1, RAD54L | MAPT 2363/4885ALDH1A1 2196/4885MEN1 2712/4885 |
| US-20110294848-A1 | SMALL MOLECULE INHIBITORS OF BOTULINUM NEUROTOXINS | RAC2, BTN3A1, GDI1 | MAPT 2064/4885ALDH1A1 4398/4885MEN1 2424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.