Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | P4HB | P07237 | 3/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341664 | 1.00 | TYR (0.60) | TYRMAPTMAPK1GABRA3GABRA2 | |
| SCHEMBL10341634 | 0.90 | CHRNA7 (0.64) | TYRMAPTGABRA3GABRA2GABRB2 | |
| SCHEMBL10341635 | 0.90 | CHRNA7 (0.64) | TYRMAPTGABRA3GABRA2GABRB2 | |
| SCHEMBL1659465 | 0.85 | TYR (0.77) | TYRMAPTCAPN1CTSLCTSB | |
| SCHEMBL1659468 | 0.85 | TYR (0.77) | TYRMAPTCAPN1CTSLCTSB | |
| SCHEMBL9819142 | 0.84 | AR (0.64) | TYRMAPTMAPK1GABRA3GABRA2 | |
| SCHEMBL7925087 | 0.84 | MAPT (0.53) | TYRMAPTP4HBLMNABCHE | |
| SCHEMBL29837087 | 0.84 | AR (0.64) | TYRMAPTMAPK1GABRA3GABRA2 | |
| SCHEMBL9819136 | 0.84 | AR (0.64) | TYRMAPTMAPK1GABRA3GABRA2 | |
| SCHEMBL7925085 | 0.84 | MAPT (0.53) | TYRMAPTP4HBLMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173748-B1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1990-01-03 | — | — | EP | claimed |
| US-4663478-A | Process for producing a para-substituted phenol derivative | Hirai, Hidefuni | 1987-05-05 | — | — | US | claimed |
| EP-0173748-A1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1986-03-12 | — | — | EP | claimed |
| EP-0173748-B1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1990-01-03 | — | — | EP | disclosed |
| US-4663478-A | Process for producing a para-substituted phenol derivative | Hirai, Hidefuni | 1987-05-05 | — | — | US | disclosed |
| EP-0173748-A1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1986-03-12 | — | — | EP | disclosed |