Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.64 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.54 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341635 | 1.00 | CHRNA7 (0.64) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL10341663 | 0.90 | TYR (0.60) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL10341664 | 0.90 | TYR (0.60) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL1659465 | 0.82 | TYR (0.77) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL1659468 | 0.82 | TYR (0.77) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL21437655 | 0.81 | CHRNA7 (0.75) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL4362328 | 0.79 | CTSL (0.64) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL9250766 | 0.78 | MAPT (0.76) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL1695381 | 0.78 | CHRNA7 (1.00) | CHRNA7CAPN1CTSLCTSBTYR | |
| SCHEMBL1695380 | 0.78 | CHRNA7 (1.00) | CHRNA7CAPN1CTSLCTSBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173748-B1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1990-01-03 | — | — | EP | disclosed |
| US-4663478-A | Process for producing a para-substituted phenol derivative | Hirai, Hidefuni | 1987-05-05 | — | — | US | disclosed |
| EP-0173748-A1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1986-03-12 | — | — | EP | disclosed |