SCHEMBL10344489

SCHEMBL10344489

O=c1oc(-c2cccc(C(F)(F)F)c2)nc2cccc([N+](=O)[O-])c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
ELANE P08246 2/20 0.49
NOTUM Q6P988 2/20 0.45
PBRM1 Q86U86 1/20 0.45
MAPT P10636 4/20 0.44
F2 P00734 1/20 0.44
C1R P00736 1/20 0.44
KLK3 P07288 1/20 0.42
EIF4E P06730 1/20 0.41
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
UTRN P46939 1/20 0.41
PGR P06401 1/20 0.39
RAB9A P51151 2/20 0.39
ABCG2 Q9UNQ0 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489848 0.83 MEN1 (0.58) MEN1KMT2AELANEPBRM1MAPT
SCHEMBL17770598 0.83 MEN1 (0.58) MEN1KMT2AELANEPBRM1MAPT
SCHEMBL465868 0.83 MEN1 (0.50) MEN1KMT2AELANENOTUMMAPT
SCHEMBL7186075 0.82 F7 (0.54) KMT2AELANENOTUMPBRM1MAPT
SCHEMBL912820 0.81 PBRM1 (0.67) ELANENOTUMPBRM1C1RF7
SCHEMBL10344443 0.77 ELANE (0.66) MEN1KMT2AELANENOTUMMAPT
SCHEMBL914145 0.76 F7 (0.59) MEN1KMT2AELANEMAPTF2
SCHEMBL912480 0.75 KMT2A (0.73) MEN1KMT2AELANEMAPTF2
SCHEMBL3206088 0.74 RAB9A (0.70) MEN1KMT2AELANEMAPTL3MBTL1
SCHEMBL10344581 0.73 PBRM1 (0.50) MEN1KMT2AELANENOTUMPBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0121129-B1 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES BASF Aktiengesellschaft (DE) 1989-02-01 EP disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
EP-0115808-B1 CYCLOHEXAN-1,3-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1986-08-20 EP disclosed
EP-0084665-B1 THIADIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN COMBATTING UNWANTED PLANT GROWTH BASF Aktiengesellschaft (DE) 1986-08-13 EP disclosed
EP-0104389-B1 QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE CONTROL OF UNDESIRED PLANT GROWTH BASF Aktiengesellschaft (DE) 1986-07-16 EP disclosed
US-4585881-A 2,5-dihydro-5-aryliminopyrrole derivatives and their preparation BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed
EP-0067382-B1 N-CYCLOHEXYL-CHLOROACETAMIDES, THEIR PREPARATION AND THEIR USE IN COMBATING UNDESIRED PLANT GROWTH BASF Aktiengesellschaft (DE) 1985-12-04 EP disclosed
US-4494983-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1985-01-22 US disclosed
EP-0121129-A1 2,5-Dihydro-5-arylimino-pyrroles, process for their production and their uses as herbicides BASF Aktiengesellschaft (DE) 1984-10-10 EP disclosed
EP-0115808-A1 Cyclohexan-1,3-dione derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1984-08-15 EP disclosed
US-4422864-A Cyclohexanedione derivatives, their preparation and herbicides containing them BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0084665-A1 Thiadiazole derivatives, process for their preparation, and their use in combatting unwanted plant growth BASF Aktiengesellschaft (DE) 1983-08-03 EP disclosed
EP-0071707-A1 Cyclohexane-dione derivatives, process for their preparation and herbicides containing them BASF Aktiengesellschaft (DE) 1983-02-16 EP disclosed
EP-0070370-A1 Cyclohexane-dione derivatives, process for their preparation and herbicides containing them BASF Aktiengesellschaft (DE) 1983-01-26 EP disclosed
EP-0067382-A2 N-cyclohexyl-chloroacetamides, their preparation and their use in combating undesired plant growth BASF Aktiengesellschaft (DE) 1982-12-22 EP disclosed
EP-0053678-A1 5-Amino-1-phenyl-4-cyano pyrazoles, herbicides containing them, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-06-16 EP disclosed