SCHEMBL10344503

SCHEMBL10344503

O=c1oc(-c2ccc(OC(F)(F)Cl)cc2)nc2cccc(F)c12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.47
MAPT P10636 4/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 3/20 0.41
PBRM1 Q86U86 1/20 0.41
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
F7 P08709 2/20 0.38
F3 P13726 2/20 0.38
C1R P00736 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
TRPV4 Q9HBA0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10967915 0.90 NOTUM (0.47) ELANEMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10594235 0.88 ALDH1A1 (0.47) ELANEMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10344681 0.88 PBRM1 (0.55) ELANEMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10596808 0.87 ELANE (0.44) ELANEMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL17554151 0.83 KDM4E (0.64) ELANEMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10596810 0.81 ELANE (0.43) ELANEMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL11002682 0.81 F7 (0.53) ELANEMAPTNPC1RAB9APBRM1
SCHEMBL10344530 0.81 MAPT (0.54) ELANEMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL203587 0.79 ELANE (0.61) ELANEMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10595299 0.79 ALDH1A1 (0.49) ELANEMAPTSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0121129-B1 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES BASF Aktiengesellschaft (DE) 1989-02-01 EP disclosed
EP-0136646-B1 PROCESS FOR THE PREPARATION OF 5-FLUOR-4H-3,1-BENZOXAZIN-4-ONES BASF Aktiengesellschaft (DE) 1989-01-25 EP disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
EP-0115808-B1 CYCLOHEXAN-1,3-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1986-08-20 EP disclosed
EP-0084665-B1 THIADIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN COMBATTING UNWANTED PLANT GROWTH BASF Aktiengesellschaft (DE) 1986-08-13 EP disclosed
US-4585881-A 2,5-dihydro-5-aryliminopyrrole derivatives and their preparation BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed
EP-0170203-A2 4H-Pyrido(2,3-d)(1,3)oxazin-4-one derivatives, process for their preparation, and their use for combating undesired vegetation BASF Aktiengesellschaft (DE) 1986-02-05 EP disclosed
EP-0136646-A2 Process for the preparation of 5-fluor-4H-3,1-benzoxazin-4-ones BASF Aktiengesellschaft (DE) 1985-04-10 EP disclosed
US-4494983-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1985-01-22 US disclosed
EP-0121129-A1 2,5-Dihydro-5-arylimino-pyrroles, process for their production and their uses as herbicides BASF Aktiengesellschaft (DE) 1984-10-10 EP disclosed
EP-0115808-A1 Cyclohexan-1,3-dione derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1984-08-15 EP disclosed
US-4422864-A Cyclohexanedione derivatives, their preparation and herbicides containing them BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0084665-A1 Thiadiazole derivatives, process for their preparation, and their use in combatting unwanted plant growth BASF Aktiengesellschaft (DE) 1983-08-03 EP disclosed
EP-0071707-A1 Cyclohexane-dione derivatives, process for their preparation and herbicides containing them BASF Aktiengesellschaft (DE) 1983-02-16 EP disclosed
EP-0070370-A1 Cyclohexane-dione derivatives, process for their preparation and herbicides containing them BASF Aktiengesellschaft (DE) 1983-01-26 EP disclosed
EP-0067382-A2 N-cyclohexyl-chloroacetamides, their preparation and their use in combating undesired plant growth BASF Aktiengesellschaft (DE) 1982-12-22 EP disclosed
EP-0053678-A1 5-Amino-1-phenyl-4-cyano pyrazoles, herbicides containing them, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-06-16 EP disclosed