Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344966 | 0.83 | MEN1 (0.58) | TSHRAPEX1 | |
| SCHEMBL10800714 | 0.81 | TSHR (0.61) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL10344488 | 0.81 | TSHR (0.51) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL1740872 | 0.79 | TDP1 (0.55) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL687878 | 0.78 | TSHR (0.79) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL11121919 | 0.76 | PTPN11 (0.47) | — | |
| SCHEMBL4770587 | 0.75 | TSHR (0.68) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL9931611 | 0.74 | TSHR (0.45) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL10344612 | 0.74 | APEX1 (0.51) | TSHRAPEX1ROCK2ROCK1 | |
| SCHEMBL1419142 | 0.73 | TSHR (0.50) | TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192111-B1 | ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1990-05-16 | — | — | EP | disclosed |
| US-4692187-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0192111-A1 | Iso-ureas, processes for their production and their use as herbicides | BASF Aktiengesellschaft (DE) | 1986-08-27 | — | — | EP | disclosed |