Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344720 | 0.81 | TSHR (0.53) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL2683899 | 0.80 | SMN1; SMN2 (0.50) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL10800714 | 0.79 | TSHR (0.61) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL687878 | 0.77 | TSHR (0.79) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL12292880 | 0.76 | TSHR (0.66) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL10344806 | 0.75 | APEX1 (0.50) | TSHRAPEX1TP53HTT | |
| SCHEMBL9931611 | 0.73 | TSHR (0.45) | TSHRAPEX1CA12CA1CA2 | |
| SCHEMBL10344815 | 0.72 | SMN1; SMN2 (0.52) | TSHRHTT | |
| SCHEMBL1419142 | 0.71 | TSHR (0.50) | TSHRAPEX1TP53 | |
| SCHEMBL10337709 | 0.71 | TSHR (0.59) | TSHRAPEX1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192111-B1 | ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1990-05-16 | — | — | EP | disclosed |
| US-4692187-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0192111-A1 | Iso-ureas, processes for their production and their use as herbicides | BASF Aktiengesellschaft (DE) | 1986-08-27 | — | — | EP | disclosed |