Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790315 | 0.82 | SLC6A2 (0.50) | SLC6A2TAAR1SMN1; SMN2HIF1AEPHX1 | |
| SCHEMBL3663463 | 0.82 | SLC6A2 (0.56) | SLC6A2TAAR1SMN1; SMN2HIF1AEPHX1 | |
| SCHEMBL18426836 | 0.82 | SLC6A2 (0.56) | SLC6A2TAAR1SMN1; SMN2HIF1AEPHX1 | |
| SCHEMBL28819443 | 0.80 | TAAR1 (0.48) | SLC6A2TAAR1SMN1; SMN2HIF1AEPHX1 | |
| Hydrochloric Acid SCHEMBL29101372 | 0.77 | SMN1; SMN2 (0.50) | SLC6A2TAAR1SMN1; SMN2HIF1AEPHX1 | |
| SCHEMBL10503241 | 0.76 | TAAR1 (0.67) | SLC6A2TAAR1SMN1; SMN2HIF1AEPHX1 | |
| SCHEMBL22459077 | 0.74 | SLC6A2 (0.52) | SLC6A2TAAR1SMN1; SMN2HIF1AMAOA | |
| SCHEMBL352842 | 0.74 | TAAR1 (0.64) | SLC6A2TAAR1SMN1; SMN2HIF1AEPHX1 | |
| SCHEMBL4081566 | 0.74 | TAAR1 (0.64) | SLC6A2TAAR1SMN1; SMN2HIF1AMAOA | |
| SCHEMBL583541 | 0.74 | TAAR1 (0.64) | SLC6A2TAAR1SMN1; SMN2HIF1AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012115984-A2 | POLYURETHANE DISPERSIONS AND METHODS OF MAKING AND USING SAME | FELICE KRISTOPHER M (US) | 2012-08-30 | — | — | WO | disclosed |
| EP-0354471-A1 | Use of aqueous polyurethane dispersions as domestic universal adhesive and their preparation | Henkel Kommanditgesellschaft auf Aktien (DE) | 1990-02-14 | — | — | EP | disclosed |