Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389180 | 0.85 | TSHR (0.63) | TSHRALDH1A1CETPKDM4EFOLH1 | |
| SCHEMBL17357035 | 0.84 | TSHR (0.53) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL27969393 | 0.84 | TSHR (0.53) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11538617 | 0.81 | TSHR (0.70) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL4586560 | 0.81 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL4586530 | 0.81 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8619121 | 0.79 | TSHR (0.57) | TSHRALDH1A1CETPKDM4EFOLH1 | |
| SCHEMBL7336647 | 0.78 | TSHR (0.51) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL4586535 | 0.78 | TSHR (0.47) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL17034260 | 0.78 | TSHR (0.55) | TSHRMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101441-A1 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | Human BioMolecular Research Foundation (US) | 2017-04-13 | — | — | US | disclosed |
| US-9549991-B2 | Chemical and biochemical adducts as biomarkers for organophosphate exposure | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2017-01-24 | — | — | US | disclosed |
| EP-2276510-B1 | Chemical and biochemical adducts as biomarkers for organophosphate exposure | HUMAN BIOMOLECULAR RES INST (US) | 2016-07-06 | — | — | EP | disclosed |
| US-20110236931-A1 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2011-09-29 | — | — | US | disclosed |
| EP-2276510-A2 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | Human Biomolecular Research Institute (US) | 2011-01-26 | — | — | EP | disclosed |
| WO-2010039163-A2 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110236931-A1 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | AOX1, PTMS, GSTA2 | TSHR 4071/4885MEN1 4064/4885KMT2A 1744/4885 |
| US-20170101441-A1 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | PTMS, OGFRL1, AOX1 | TSHR 1766/4885MEN1 4227/4885KMT2A 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.