Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.56 |
| ▸ | PPARD | Q03181 | 6/20 | 0.56 |
| ▸ | PPARA | Q07869 | 6/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126245 | 1.00 | CES2 (0.59) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL6136621 | 1.00 | CES2 (0.59) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL11124207 | 1.00 | CES2 (0.59) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL7319924 | 0.98 | CES2 (0.56) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL28140535 | 0.88 | CES2 (0.67) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL10590670 | 0.85 | CES2 (0.62) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL15361606 | 0.82 | CES2 (0.59) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL28110135 | 0.82 | CES2 (0.59) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL8088901 | 0.82 | CES2 (0.59) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL28377127 | 0.81 | CES2 (0.58) | CES2GPR84TSHRALDH1A1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137301-B1 | 2-KETOCARBOXYLIC-ACID REDUCTASE, ITS PREPARATION AND ITS USE | BASF Aktiengesellschaft (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4622301-A | DISINTEGRATION OF PROTEUS | BASF AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |
| EP-0137301-A2 | 2-Ketocarboxylic-acid reductase, its preparation and its use | BASF Aktiengesellschaft (DE) | 1985-04-17 | — | — | EP | disclosed |
| EP-0043173-B1 | BLEACHING COMPOSITIONS, DETERGENT PRODUCTS CONTAINING SAME AND PROCESS FOR THEIR USE | THE PROCTER & GAMBLE COMPANY (US) | 1984-07-25 | — | — | EP | disclosed |
| US-4367156-A | PEROXYGEN COMPOUND ACTIVATED BY LONG CHAIN ACYL COMPOUND WITH QUATERNARY IMIDAZOLE GROUP | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-04 | — | — | US | disclosed |
| EP-0043173-A1 | Bleaching compositions, detergent products containing same and process for their use | THE PROCTER & GAMBLE COMPANY (US) | 1982-01-06 | — | — | EP | disclosed |
| US-4283301-A | COMPRISING A PEROXY BLEACH, ACTIVATOR | THE PROCTER & GAMBLE COMPANY (US) | 1981-08-11 | — | — | US | disclosed |