SCHEMBL7319924

SCHEMBL7319924

CCCCCC(=O)C(C(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.56
AKR1B1 P15121 1/20 0.54
GPR84 Q9NQS5 6/20 0.52
PPARG P37231 6/20 0.52
PPARD Q03181 6/20 0.52
PPARA Q07869 6/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
PTPN1 P18031 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52
ESR1 P03372 1/20 0.52
ALOX15 P16050 1/20 0.52
PDE4A P27815 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11126245 0.98 CES2 (0.59) CES2GPR84PPARGPPARDPPARA
SCHEMBL11124207 0.98 CES2 (0.59) CES2GPR84PPARGPPARDPPARA
SCHEMBL6136621 0.98 CES2 (0.59) CES2GPR84PPARGPPARDPPARA
SCHEMBL10344895 0.98 CES2 (0.59) CES2GPR84PPARGPPARDPPARA
SCHEMBL10590670 0.87 CES2 (0.62) CES2AKR1B1GPR84PPARGPPARD
SCHEMBL28140535 0.85 CES2 (0.67) CES2GPR84PPARGPPARDPPARA
SCHEMBL28377127 0.83 CES2 (0.58) CES2AKR1B1GPR84TSHRALDH1A1
SCHEMBL4940589 0.82 HDAC1 (0.48) CES2AKR1B1GPR84PPARGPPARD
SCHEMBL3142041 0.79 CES2 (0.54) CES2AKR1B1GPR84PPARGPPARD
SCHEMBL3820001 0.79 CES2 (0.54) CES2AKR1B1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0043173-B1 BLEACHING COMPOSITIONS, DETERGENT PRODUCTS CONTAINING SAME AND PROCESS FOR THEIR USE THE PROCTER & GAMBLE COMPANY (US) 1984-07-25 EP claimed
EP-0043173-A1 Bleaching compositions, detergent products containing same and process for their use THE PROCTER & GAMBLE COMPANY (US) 1982-01-06 EP claimed
US-4283301-A COMPRISING A PEROXY BLEACH, ACTIVATOR THE PROCTER & GAMBLE COMPANY (US) 1981-08-11 US claimed
EP-1230225-A2 PHARMACEUTICALLY ACTIVE 4-SUBSTITUTED PYRIMIDINE DERIVATIVES ELI LILLY AND COMPANY (US) 2002-08-14 EP disclosed
WO-2001032632-A2 PHARMACEUTICALLY ACTIVE 4-SUBSTITUTED PYRIMIDINE DERIVATIVES ELI LILLY AND COMPANY (US) 2001-05-10 WO disclosed
EP-0610439-B1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PROD (US) 1999-12-15 EP disclosed
EP-0610439-A1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1994-08-17 EP disclosed
US-5234936-A Treating hypertension, congestive heart failure, hyperlipidemia and hypercholesterolemia AMERICAN HOME PRODUCTS CORPORATION (US) 1993-08-10 US disclosed
WO-1993008171-A1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1993-04-29 WO disclosed
EP-0157567-B1 CARBOXY-CONTAINING ESTER PRODRUGS OF CORTICOSTEROIDS THE UPJOHN COMPANY (US) 1989-11-29 EP disclosed
US-4588718-A ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1986-05-13 US disclosed
EP-0157567-A2 Carboxy-containing ester prodrugs of corticosteroids THE UPJOHN COMPANY (US) 1985-10-09 EP disclosed
EP-0043173-B1 BLEACHING COMPOSITIONS, DETERGENT PRODUCTS CONTAINING SAME AND PROCESS FOR THEIR USE THE PROCTER & GAMBLE COMPANY (US) 1984-07-25 EP disclosed
US-4367156-A PEROXYGEN COMPOUND ACTIVATED BY LONG CHAIN ACYL COMPOUND WITH QUATERNARY IMIDAZOLE GROUP THE PROCTER & GAMBLE COMPANY (US) 1983-01-04 US disclosed
EP-0005422-B1 DERIVATIVES OF OMEGA-DIALKYLALKANOIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE SANOFI S.A. (FR) 1982-10-27 EP disclosed
EP-0043173-A1 Bleaching compositions, detergent products containing same and process for their use THE PROCTER & GAMBLE COMPANY (US) 1982-01-06 EP disclosed
US-4283301-A COMPRISING A PEROXY BLEACH, ACTIVATOR THE PROCTER & GAMBLE COMPANY (US) 1981-08-11 US disclosed
EP-0005422-A2 Derivatives of omega-dialkylalkanoic acids, processes for their preparation and their therapeutical use SANOFI S.A. (FR) 1979-11-14 EP disclosed