Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPR3 | P17342 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10490553 | 0.98 | HDAC1 (0.40) | HDAC1ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL10345301 | 0.88 | ADORA1 (0.42) | HDAC1ADORA3ADORA1ADORA2ACYP2C9 | |
| SCHEMBL17451135 | 0.85 | ADORA3 (0.49) | ADORA3ADORA1ADORA2AADORA2BMAPK1 | |
| SCHEMBL10345111 | 0.85 | KMT2A (0.42) | ADORA1MEN1MAPTKMT2A | |
| SCHEMBL10345100 | 0.84 | HDAC1 (0.41) | HDAC1CYP2C9NPR3CYP2C19MEN1 | |
| SCHEMBL10345096 | 0.83 | HDAC1 (0.40) | HDAC1ADORA3ADORA1CYP2C9NPR3 | |
| SCHEMBL3295887 | 0.82 | ADORA3 (0.49) | ADORA3ADORA1ADORA2AADORA2BMAPK1 | |
| SCHEMBL10618577 | 0.81 | CYP2C9 (0.40) | HDAC1CYP2C9NPR3CYP2C19MAPT | |
| SCHEMBL10618588 | 0.80 | CYP2C9 (0.40) | HDAC1CYP2C9NPR3CYP2C19CDK4 | |
| SCHEMBL17899113 | 0.79 | ADORA3 (0.44) | ADORA3ADORA1ADORA2AADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145660-B1 | INSECTICIDAL COMPOSITION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | claimed |
| US-4824845-A | CONTROLLING ECTOPARASITES IN ANIMALS | CIBA-GEIGY CORPORATION (US) | 1989-04-25 | — | — | US | claimed |
| EP-0145660-A2 | Insecticidal composition | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | claimed |
| EP-0145660-B1 | INSECTICIDAL COMPOSITION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |
| US-4824845-A | CONTROLLING ECTOPARASITES IN ANIMALS | CIBA-GEIGY CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0145660-A2 | Insecticidal composition | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |