Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPR3 | P17342 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345263 | 0.93 | CYP2C19 (0.44) | CYP2C9NPR3CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL10345102 | 0.84 | HDAC1 (0.41) | HDAC1CYP2C9NPR3CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL10490553 | 0.83 | HDAC1 (0.40) | HDAC1CYP2C9NPR3CYP2C19MEN1 | |
| SCHEMBL10618588 | 0.82 | CYP2C9 (0.40) | HDAC1CYP2C9NPR3CYP2C19NPSR1 | |
| SCHEMBL10345301 | 0.82 | ADORA1 (0.42) | HDAC1CYP2C9NPR3CYP2C19 | |
| SCHEMBL10345096 | 0.79 | HDAC1 (0.40) | HDAC1CYP2C9NPR3CYP2C19ALDH1A1 | |
| SCHEMBL10345111 | 0.78 | KMT2A (0.42) | ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL10618577 | 0.78 | CYP2C9 (0.40) | HDAC1CYP2C9NPR3CYP2C19NPSR1 | |
| SCHEMBL10345105 | 0.75 | CYP2C9 (0.40) | HDAC1CYP2C9NPR3CYP2C19NPSR1 | |
| SCHEMBL10706738 | 0.74 | NUDT1 (0.43) | HDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145660-B1 | INSECTICIDAL COMPOSITION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | claimed |
| EP-0145660-A2 | Insecticidal composition | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | claimed |
| EP-0145660-B1 | INSECTICIDAL COMPOSITION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |
| US-4824845-A | CONTROLLING ECTOPARASITES IN ANIMALS | CIBA-GEIGY CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0145660-A2 | Insecticidal composition | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |