Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420619 | 0.91 | MAPT (0.56) | HTTPOLBMAPTALDH1A1MCOLN3 | |
| SCHEMBL283988 | 0.84 | ALDH1A1 (0.52) | HTTPOLBMAPTALDH1A1MCOLN3 | |
| SCHEMBL11503790 | 0.82 | ALDH1A1 (0.50) | HTTPOLBMAPTALDH1A1MCOLN3 | |
| Hydrochloric Acid SCHEMBL28554078 | 0.82 | ALDH1A1 (0.50) | HTTPOLBMAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL451487 | 0.82 | ALDH1A1 (0.50) | HTTPOLBMAPTALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL1608735 | 0.82 | ALDH1A1 (0.50) | HTTPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13490256 | 0.82 | ALDH1A1 (0.50) | HTTPOLBMAPTALDH1A1MCOLN3 | |
| SCHEMBL27676423 | 0.78 | GAA (0.46) | HTTPOLBMAPTALDH1A1SMN1; SMN2 | |
| Toluene SCHEMBL23630013 | 0.78 | MAPT (0.44) | HTTPOLBMAPTALDH1A1LMNA | |
| SCHEMBL30874625 | 0.77 | HTT (0.46) | HTTPOLBMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227936-B1 | LUMINESCENT PALLADIUM(0) AND PLATINUM(0) CARBENE COMPLEXES FOR OLEDS | UNIV COURT UNIV ST ANDREWS (GB) | 2018-07-25 | — | — | EP | disclosed |
| US-8877936-B2 | Ruthenium olefin metathesis catalysts bearing N-heterocyclic carbene ligands with substituted backbone | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-11-04 | — | — | US | disclosed |
| US-8361922-B2 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | MATERIA, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8222265-B2 | Six-membered N-heterocyclic carbene-based catalysts for asymmetric reactions | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-07-17 | — | — | US | disclosed |
| US-20110054170-A1 | Six-membered N-Heterocyclic Carbene-based catalysts for asymmetric reactions | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-03-03 | — | — | US | disclosed |
| US-20100210515-A1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | AILERON THERAPEUTICS, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| US-20070282148-A1 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070282148-A1 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | ORC3, OXER1, CBR3 | HTT 1107/4885POLB 2244/4885MAPT 2228/4885 |
| US-20100210515-A1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | VIP, NGLY1, IAPP | HTT 715/4885POLB 2612/4885MAPT 3949/4885 |
| US-20110054170-A1 | Six-membered N-Heterocyclic Carbene-based catalysts for asymmetric reactions | NIT2, GNE, NISCH | HTT 3742/4885POLB 2404/4885MAPT 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.