SCHEMBL283988

SCHEMBL283988

Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2)c(C)c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
MAPT P10636 3/20 0.52
NPSR1 Q6W5P4 2/20 0.52
POLB P06746 2/20 0.52
HTT P42858 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HRH3 Q9Y5N1 1/20 0.36
RAPGEF4 Q8WZA2 1/20 0.35
KDM4E B2RXH2 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTR1A P08908 2/20 0.34
HTR3A P46098 2/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CRHR1 P34998 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL451487 0.98 ALDH1A1 (0.50) ALDH1A1MAPTNPSR1POLBHTT
Bromide SCHEMBL1608735 0.98 ALDH1A1 (0.50) ALDH1A1MAPTNPSR1POLBHTT
Hydrochloric Acid SCHEMBL28554078 0.98 ALDH1A1 (0.50) ALDH1A1MAPTNPSR1POLBHTT
SCHEMBL30874625 0.91 HTT (0.46) ALDH1A1MAPTNPSR1POLBHTT
SCHEMBL16307952 0.91 ALDH1A1 (0.53) ALDH1A1MAPTNPSR1POLBHTT
SCHEMBL6494829 0.91 ALDH1A1 (0.49) ALDH1A1MAPTNPSR1POLBHTT
SCHEMBL20106885 0.90 ALDH1A1 (0.60) ALDH1A1MAPTNPSR1POLBHTT
SCHEMBL16078010 0.89 MAPT (0.45) ALDH1A1MAPTNPSR1POLBHTT
SCHEMBL18122718 0.89 HTT (0.45) ALDH1A1MAPTNPSR1POLBHTT
Bromide SCHEMBL1609046 0.89 ALDH1A1 (0.47) ALDH1A1MAPTNPSR1POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1735 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025034579-A1 METHODS FOR PREPARATION OF BIOCOMPATIBLE SOLUTIONS WITH SABRE HYPERPOLARIZATION VIZMA LIFE SCIENCES, INC. (US) 2025-02-13 WO claimed
EP-3016991-B1 LIQUID MOLDING COMPOSITIONS MATERIA INC (US) 2024-06-12 EP claimed
EP-4139281-B1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES UNIV HEIDELBERG (DE) 2024-05-08 EP claimed
US-20240116039-A1 RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE UMICORE AG & CO. KG (DE) 2024-04-11 US claimed
EP-4288479-A1 LONG SHELF LIFE STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2023-12-13 EP claimed
EP-3256505-B1 CYCLIC OLEFIN RESIN COMPOSITIONS COMPRISING FUNCTIONAL ELASTOMERS MATERIA INC (US) 2023-11-29 EP claimed
US-11821112-B1 Polymer fibers and particles produced by electrospinning or electrospraying SCALE HOLDINGS LLC (US) 2023-11-21 US claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 CN claimed
CN-116162096-A Preparation method of benzo [6,6] -spiroketal compound 五邑大学 2023-05-26 CN claimed
US-20230149911-A1 RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE UMICORE AG & CO. KG (DE) 2023-05-18 US claimed
US-20060128935-A1 Manufacture of macrocyclic polyester oligomers E. I. DU PONT DE NEMOURS AND COMPANY 2006-06-15 US claimed
US-20060128912-A1 Transition metal carbene complexes containing a cationic substituent as catalysts of olefin metathesis reactions UTI LIMITED PARTNERSHIP (CA) 2006-06-15 US claimed
US-7002049-B2 Process for α,β-dihydroxyalkenes and derivatives EASTMAN CHEMICAL COMPANY (US) 2006-02-21 US claimed
US-20060030742-A1 Process for alpha,beta-dihydroxyalkenes and derivatives HEMBRE ROBERT T 2006-02-09 US claimed
WO-2005121158-A1 TRANSITION METAL CARBENE COMPLEXES CONTAINING A CATIONIC SUBSTITUENT AS CATALYSTS OF OLEFIN METATHESIS REACTIONS UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2005-12-22 WO claimed
WO-2005063834-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-07-14 WO claimed
US-20050137369-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2005-06-23 US claimed
US-20050131233-A1 Ruthenium compounds, their production and use UNIVERSITY OF OTTAWA (CA) 2005-06-16 US claimed
WO-2005012315-A1 RUTHENIUM COMPOUNDS, THEIR PRODUCTION AND USE UNIVERSITY OF OTTAWA (CA) 2005-02-10 WO claimed
US-20040044229-A1 Process for alpha,beta-dihydroxyalkenes and derivatives HEMBRE ROBERT THOMAS (US) 2004-03-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044229-A1 Process for alpha,beta-dihydroxyalkenes and derivatives CYP8B1, EBP, DEGS1 ALDH1A1 226/4885MAPT 2680/4885NPSR1 2074/4885
US-20060128912-A1 Transition metal carbene complexes containing a cationic substituent as catalysts of olefin metathesis reactions SOD1, OPRM1, C1S ALDH1A1 3136/4885MAPT 3686/4885NPSR1 2641/4885
US-20050131233-A1 Ruthenium compounds, their production and use TIPARP, SPR, PARP14 ALDH1A1 775/4885MAPT 3504/4885NPSR1 3265/4885
US-20060030742-A1 Process for alpha,beta-dihydroxyalkenes and derivatives CYP8B1, EBP, DHCR24 ALDH1A1 195/4885MAPT 2197/4885NPSR1 2175/4885
US-20230149911-A1 RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE HMBS, RRP12, RNF168 ALDH1A1 844/4885MAPT 1360/4885NPSR1 4751/4885
US-20240116039-A1 RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE HMBS, RRP12, RNF168 ALDH1A1 844/4885MAPT 1360/4885NPSR1 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.