Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953059 | 0.90 | SQOR (0.36) | SQORESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8953066 | 0.90 | SQOR (0.36) | SQORESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8952989 | 0.83 | SQOR (0.44) | SQORESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL10345240 | 0.83 | HMGCR (0.39) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL8952796 | 0.82 | — | — | |
| SCHEMBL8952806 | 0.82 | — | — | |
| SCHEMBL9849260 | 0.82 | — | — | |
| SCHEMBL8953052 | 0.82 | — | — | |
| SCHEMBL10345348 | 0.81 | NR4A2 (0.42) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL8952794 | 0.78 | SQOR (0.32) | SQORKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356788-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0356788-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1990-03-07 | — | — | EP | disclosed |