Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345875 | 0.90 | FDPS (0.53) | FDPS | |
| SCHEMBL10346155 | 0.74 | FDPS (0.45) | FDPS | |
| SCHEMBL13235827 | 0.74 | FDPS (0.53) | FDPS | |
| SCHEMBL10346154 | 0.69 | FDPS (0.84) | FDPS | |
| SCHEMBL10345500 | 0.69 | FDPS (0.49) | FDPS | |
| SCHEMBL2203676 | 0.69 | FDPS (0.85) | FDPS | |
| SCHEMBL2472093 | 0.67 | FDPS (1.00) | FDPS | |
| N-(Hexamethyleneimino)Methylenebisphosphonic Acid SCHEMBL12309768 | 0.67 | FDPS (1.00) | FDPS | |
| SCHEMBL10345518 | 0.67 | FDPS (0.46) | FDPS | |
| SCHEMBL10345929 | 0.66 | FDPS (0.32) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248854-B1 | NOVEL BISPHOSPHONIC DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1990-04-25 | — | — | EP | disclosed |
| US-4870063-A | Bisphosphonic acid derivatives, their production and use | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1989-09-26 | — | — | US | disclosed |