Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPR3 | P17342 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345096 | 0.91 | HDAC1 (0.40) | POLBCYP1A2L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL3299561 | 0.80 | POLB (0.62) | POLBCYP1A2L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL11474745 | 0.78 | PDE4A (0.48) | CYP2C9CYP2C19NPR3PDE4ARAB9A | |
| SCHEMBL10345263 | 0.75 | CYP2C19 (0.44) | CYP2C9CYP2C19NPR3ALDH1A1RAB9A | |
| SCHEMBL10618588 | 0.74 | CYP2C9 (0.40) | CYP2C9CYP2C19NPR3PDE4ABRAF | |
| SCHEMBL10345102 | 0.73 | HDAC1 (0.41) | CYP2C9CYP2C19NPR3ADORA3ADORA1 | |
| SCHEMBL10345105 | 0.73 | CYP2C9 (0.40) | CYP2C9CYP2C19NPR3ADORA1ALDH1A1 | |
| SCHEMBL10616777 | 0.72 | CYP2C9 (0.50) | CYP2C9CYP2C19NPR3ALDH1A1ACACB | |
| Hydrochloric Acid SCHEMBL10490553 | 0.72 | HDAC1 (0.40) | CYP2C9CYP2C19NPR3ADORA3ADORA1 | |
| SCHEMBL12766932 | 0.72 | POLB (0.54) | POLBCYP1A2L3MBTL1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145660-B1 | INSECTICIDAL COMPOSITION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |
| US-4824845-A | CONTROLLING ECTOPARASITES IN ANIMALS | CIBA-GEIGY CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0145660-A2 | Insecticidal composition | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |