Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPR3 | P17342 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345100 | 0.93 | HDAC1 (0.41) | CYP2C19CYP2C9NPR3NPSR1ALDH1A1 | |
| SCHEMBL10345557 | 0.75 | POLB (0.46) | CYP2C19CYP2C9NPR3ALDH1A1RAB9A | |
| SCHEMBL10345102 | 0.75 | HDAC1 (0.41) | CYP2C19CYP2C9NPR3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10490553 | 0.74 | HDAC1 (0.40) | CYP2C19CYP2C9NPR3MEN1KMT2A | |
| SCHEMBL10618588 | 0.73 | CYP2C9 (0.40) | CYP2C19CYP2C9NPR3NPSR1SMN1; SMN2 | |
| SCHEMBL10345301 | 0.73 | ADORA1 (0.42) | CYP2C19CYP2C9NPR3KDM4EMAPT | |
| SCHEMBL10616777 | 0.71 | CYP2C9 (0.50) | CYP2C19CYP2C9NPR3ALDH1A1MEN1 | |
| SCHEMBL10345111 | 0.70 | KMT2A (0.42) | ALDH1A1MEN1KMT2ARAB9AGAA | |
| SCHEMBL11474745 | 0.70 | PDE4A (0.48) | CYP2C19CYP2C9NPR3NPSR1RAB9A | |
| SCHEMBL2090052 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145660-B1 | INSECTICIDAL COMPOSITION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |
| US-4824845-A | CONTROLLING ECTOPARASITES IN ANIMALS | CIBA-GEIGY CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0145660-A2 | Insecticidal composition | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |