Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345985 | 0.92 | FDPS (0.46) | FDPS | |
| SCHEMBL10345921 | 0.72 | FDPS (0.48) | FDPS | |
| SCHEMBL10345504 | 0.69 | FDPS (0.44) | FDPS | |
| SCHEMBL10345910 | 0.69 | FDPS (0.44) | FDPS | |
| SCHEMBL10346122 | 0.66 | MEN1 (0.37) | — | |
| SCHEMBL10345909 | 0.65 | FDPS (0.40) | FDPS | |
| SCHEMBL10345924 | 0.65 | FDPS (0.40) | FDPS | |
| SCHEMBL10345509 | 0.63 | S1PR1 (0.43) | FDPS | |
| SCHEMBL13235826 | 0.61 | FDPS (0.45) | FDPS | |
| Thiomorpholinomethylenediphosphonic Acid SCHEMBL1471965 | 0.61 | FDPS (1.00) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248854-B1 | NOVEL BISPHOSPHONIC DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1990-04-25 | — | — | EP | disclosed |
| US-4870063-A | Bisphosphonic acid derivatives, their production and use | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1989-09-26 | — | — | US | disclosed |
| EP-0248854-A1 | NOVEL BISPHOSPHONIC DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION. | LEO PHARM PROD LTD (DK) | 1987-12-16 | — | — | EP | disclosed |
| WO-1987003598-A1 | NOVEL BISPHOSPHONIC DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1987-06-18 | — | — | WO | disclosed |