Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | TTPA | P49638 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346651 | 0.94 | MEN1 (0.43) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL4864444 | 0.90 | PSEN1 (0.40) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL11445274 | 0.85 | PSEN1 (0.41) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL11445076 | 0.85 | PSEN1 (0.41) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL9096806 | 0.83 | MEN1 (0.39) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL8950693 | 0.81 | MEN1 (0.39) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL8950708 | 0.80 | MEN1 (0.41) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL29180347 | 0.77 | MEN1 (0.45) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL10346383 | 0.74 | MEN1 (0.46) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL10346932 | 0.74 | MEN1 (0.48) | MEN1KMT2APDE4APDE3AGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202580-B1 | 3,4-DIHYDROBENZOPYRAN DERIVATIVES | KURARAY CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| US-4728650-A | ANTIULCER, ANTITUSSIVE, EXPECTORANTS | KURARAY CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0202580-A2 | 3,4-Dihydrobenzopyran derivatives | KURARAY CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |