Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | TTPA | P49638 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950708 | 0.94 | MEN1 (0.41) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL9096806 | 0.86 | MEN1 (0.39) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL8950670 | 0.85 | ALOX5 (0.35) | CYP2C19 | |
| SCHEMBL9567467 | 0.84 | CYP2C19 (0.34) | MAPTCYP2C19 | |
| SCHEMBL9567442 | 0.84 | AKT1 (0.45) | — | |
| SCHEMBL10346387 | 0.81 | MEN1 (0.40) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL8746294 | 0.81 | MAPT (0.46) | MEN1KMT2AMAPTLMNAGSTP1 | |
| SCHEMBL8950690 | 0.81 | MAPT (0.46) | MEN1KMT2AMAPTLMNAGSTP1 | |
| SCHEMBL10346651 | 0.80 | MEN1 (0.43) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL4864444 | 0.78 | PSEN1 (0.40) | MEN1KMT2APDE4APDE3AGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7025867-A | — | — | None | — | — | JP | disclosed |
| US-5484810-A | Tissue protective tocopherol analogs | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-01-16 | — | — | US | disclosed |
| JP-H0725867-A | TISSUE PROTECTIVE TOCOPHEROLANALOG | MERRELL DOW PHARMACEUT INC | 1995-01-27 | — | — | JP | disclosed |
| EP-0550292-A1 | Tissue protective tocopherol analogs | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-07-07 | — | — | EP | disclosed |