Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445076 | 1.00 | PSEN1 (0.41) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL11445897 | 0.89 | PSEN1 (0.43) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL6978989 | 0.89 | PSEN1 (0.43) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL4864444 | 0.86 | PSEN1 (0.40) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL11445275 | 0.85 | PSEN1 (0.41) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL10346387 | 0.85 | MEN1 (0.40) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL7843080 | 0.81 | PSEN1 (0.41) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL11445899 | 0.81 | PSEN1 (0.45) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL11445900 | 0.81 | PSEN1 (0.45) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL11705307 | 0.81 | PSEN1 (0.47) | PSEN1ALOX5MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191842-A | Protected alcohols | HOFFMANN-LA ROCHE INC. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4151205-A | Synthesis of vitamin E | HOFFMAN-LA ROCHE INC. (US) | 1979-04-24 | — | — | US | disclosed |
| US-4051153-A | Intermediates in the synthesis of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1977-09-27 | — | — | US | disclosed |