SCHEMBL1034646

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034416	0.85	KMT2A (0.48)	CNR1NCS1ALDH1A1MEN1KMT2A
	SCHEMBL1033355	0.83	SCD (0.61)	BCL2L1CNR1USP2USP8DHODH
	SCHEMBL1034840	0.83	SMN1; SMN2 (0.59)	CNR1USP2USP8NCS1ALDH1A1
	SCHEMBL1031016	0.83	USP2 (0.56)	USP2USP8MEN1KMT2ASMN1; SMN2
	SCHEMBL1034065	0.83	RXFP1 (0.53)	MEN1KMT2ALMNAMAPTRAB9A
	SCHEMBL12673390	0.82	PARP1 (0.60)	BCL2L1CNR1USP2USP8NCS1
	SCHEMBL1074924	0.82	ALDH1A1 (0.52)	CNR1USP2USP8NCS1ALDH1A1
	SCHEMBL1031845	0.82	ALDH1A1 (0.45)	CNR1NCS1DHODHALDH1A1MEN1
	SCHEMBL1034835	0.82	SIRT2 (0.51)	ALDH1A1MEN1KMT2ASMN1; SMN2LMNA
	SCHEMBL1034332	0.82	SCN9A (0.49)	CNR1ALDH1A1MAPTHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.