Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 10/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.31 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28609060 | 0.83 | AR (0.31) | AR | |
| SCHEMBL145184 | 0.82 | NOTUM (0.33) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5928972 | 0.79 | TSHR (0.38) | — | |
| SCHEMBL145873 | 0.79 | AR (0.32) | NOTUMAR | |
| SCHEMBL146460 | 0.78 | AR (0.31) | AR | |
| SCHEMBL2870874 | 0.77 | CA2 (0.30) | — | |
| SCHEMBL27286478 | 0.77 | AR (0.31) | AR | |
| SCHEMBL900847 | 0.77 | — | — | |
| SCHEMBL14483362 | 0.76 | GLA (0.38) | — | |
| SCHEMBL11795286 | 0.75 | HSD11B1 (0.45) | NOTUMAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2543 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206551-A | Quinoline compounds, their preparation and their use as antimalarial agents | 美国卫生和人力服务部 | 2024-06-18 | — | — | CN | claimed |
| EP-4362949-A2 | USE OF ISOQUINOLINE-1,5-DIAMINES FOR WOUND HEALING | Lutris Pharma Ltd. (IL) | 2024-05-08 | — | — | EP | claimed |
| US-20240122933-A1 | USE OF ISOQUINOLINE-1,5-DIAMINES FOR WOUND HEALING | LUTRIS PHARMA LTD (IL) | 2024-04-18 | — | — | US | claimed |
| EP-3750894-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2024-04-03 | — | — | EP | claimed |
| US-11932609-B1 | Substituted 1,4-dihydropyrimidines as antitubercular agents | King Faisal University (SA) | 2024-03-19 | — | — | US | claimed |
| CN-116574035-B | Peach girder phenol derivative containing carbamate, preparation method and application | 扬州大学 | 2024-03-08 | — | — | CN | claimed |
| WO-2024009308-A1 | TRPV2 CHANNEL BLOCKERS AND USE THEREOF | ICHILOV TECH LTD. (IL) | 2024-01-11 | — | — | WO | claimed |
| WO-2023227734-A1 | FLAVIVIRUS INHIBITORS | IRBM S.P.A. (IT) | 2023-11-30 | — | — | WO | claimed |
| EP-3590941-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXANE-QUINAZOLINE AND -LINKED DIOXANE-QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2023-11-22 | — | — | EP | claimed |
| CN-113773263-B | 4-amine substituted phthalazinone aurora kinase B inhibitor and preparation and application thereof | 兰州大学 | 2023-09-19 | — | — | CN | claimed |
| US-4264605-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | claimed |
| US-4263296-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-21 | — | — | US | claimed |
| EP-0017976-A2 | Process for preparing imidazole derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-10-29 | — | — | EP | claimed |
| US-4200653-A | Insecticidal compound and method of use | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-04-29 | — | — | US | claimed |
| US-4197403-A | ANTIINFLAMMATORY, IMMUNOSUPPRESSIVE, FUNGICIDE | WESTWOOD PHARMACEUTICALS INC. (US) | 1980-04-08 | — | — | US | claimed |
| EP-0008881-A1 | 1-Benzoyl-3-pyridinyl ureas, their use as insecticides, their preparation and formulations containing them | ELI LILLY AND COMPANY (US) | 1980-03-19 | — | — | EP | claimed |
| WO-1980000023-A1 | SUBSTITUTED BENZOYLIMIDATES,THEIR PREPARATION AND COMPOSITIONS COMPRISING THEM FOR INSECTICIDAL USE | ICI LTD (GB) | 1980-01-10 | — | — | WO | claimed |
| EP-0005944-A1 | Substituted benzoylimidates, their preparation and compositions comprising them for insecticidal use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-12-12 | — | — | EP | claimed |
| US-4153617-A | Anorexic chromans | BEECHAM GROUP LIMITED (GB) | 1979-05-08 | — | — | US | claimed |
| US-3973010-A | Insecticidal and acaricidal composition and method with triazolyl phosphoric esters acid | CIBA-GEIGY CORPORATION (US) | 1976-08-03 | — | — | US | claimed |