Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9731185 | 0.99 | HRH3 (0.50) | HRH3KCNH2KDM4EGAAALDH1A1 | |
| SCHEMBL8719956 | 0.82 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL11028736 | 0.77 | ACE (0.55) | KDM4EGAAALDH1A1 | |
| SCHEMBL11144265 | 0.76 | PTGS1 (0.48) | HRH3KCNH2KDM4EALDH1A1 | |
| SCHEMBL17570419 | 0.75 | HRH3 (0.59) | HRH3KCNH2 | |
| SCHEMBL12414302 | 0.74 | HRH3 (0.51) | HRH3KCNH2 | |
| SCHEMBL12413672 | 0.74 | HRH3 (0.51) | HRH3KCNH2 | |
| SCHEMBL12413698 | 0.73 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL17570422 | 0.73 | OPRD1 (0.71) | HRH3 | |
| SCHEMBL10293596 | 0.72 | HRH3 (0.62) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232612-B1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS | Dr. Lo. Zambeletti S.p.A. (IT) | 1990-04-04 | — | — | EP | claimed |