Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | DRD4 | P21917 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589130 | 0.86 | OPRD1 (0.72) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| SCHEMBL10347265 | 0.86 | OPRK1 (0.76) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10560393 | 0.85 | OPRD1 (0.70) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9731645 | 0.85 | OPRK1 (0.76) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10560385 | 0.85 | OPRD1 (0.70) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| SCHEMBL6627224 | 0.83 | OPRD1 (1.00) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| SCHEMBL7641140 | 0.83 | OPRD1 (1.00) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| Fumaric Acid SCHEMBL10588799 | 0.83 | OPRD1 (0.64) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| Maleic Acid SCHEMBL10588795 | 0.83 | OPRD1 (0.64) | OPRD1OPRK1NPC1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10558194 | 0.82 | OPRD1 (0.98) | OPRD1OPRK1NPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167295-B2 | Analgesic compounds and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-01-01 | — | — | US | disclosed |
| US-20160068541-A1 | ANALGESIC COMPOUNDS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-10 | — | — | US | disclosed |
| US-20160068541-A1 | ANALGESIC COMPOUNDS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068541-A1 | ANALGESIC COMPOUNDS AND METHODS OF USE | OPRL1, OPRK1, ACHE | OPRD1 5/4885OPRK1 2/4885NPC1 1675/4885 |
| US-10167295-B2 | Analgesic compounds and methods of use | OPRL1, OPRK1, ACHE | OPRD1 5/4885OPRK1 2/4885NPC1 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.