SCHEMBL10347262

SCHEMBL10347262

CCCCCCCCCCS(=O)(=O)c1ccc(O)c(C(=O)Nc2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 4/20 0.56
TMPRSS4 Q9NRS4 2/20 0.56
SLC2A1 P11166 1/20 0.56
P2RX4 Q99571 1/20 0.56
P2RX7 Q99572 1/20 0.56
HDAC3 O15379 1/20 0.56
EGFR P00533 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CASP6 P55212 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10347260 0.89 P2RX1 (0.54) P2RX1TMPRSS4P2RX4P2RX7HDAC3
SCHEMBL10347520 0.89 P2RX1 (0.54) P2RX1TMPRSS4P2RX4P2RX7HDAC3
SCHEMBL10607741 0.81 P2RX1 (0.63) P2RX1TMPRSS4SLC2A1P2RX4P2RX7
SCHEMBL30288530 0.80 HDAC3 (0.63) P2RX1TMPRSS4SLC2A1P2RX4P2RX7
SCHEMBL29372818 0.80 HDAC3 (0.63) P2RX1TMPRSS4SLC2A1P2RX4P2RX7
SCHEMBL574259 0.80 HDAC3 (0.63) P2RX1TMPRSS4SLC2A1P2RX4P2RX7
SCHEMBL10347601 0.79 ALOX15 (0.46) P2RX1HDAC3EGFRHDAC4HDAC1
SCHEMBL10347602 0.79 ALOX15 (0.46) P2RX1HDAC3EGFRHDAC4HDAC1
SCHEMBL10347261 0.79 ALOX15 (0.46) P2RX1HDAC3EGFRHDAC4HDAC1
SCHEMBL10347139 0.77 MAPT (0.53) P2RX1TMPRSS4MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4939132-A Novel 5-alkylsulfonylsalicylanilides and microbiocidal compositions for controlling the growth of microorganisms THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-07-03 US disclosed
EP-0198366-B1 NOVEL 5-ALKYLSULFONYLSALICYLANLIDES AND MICROBIOCIDAL COMPOSITIONS FOR CONTROLLING THE GROWTH OF MICROORGANISMS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-05-09 EP disclosed
EP-0198366-A1 Novel 5-alkylsulfonylsalicylanlides and microbiocidal compositions for controlling the growth of microorganisms THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1986-10-22 EP disclosed