SCHEMBL574259

SCHEMBL574259

CCCCCCCC(=O)c1ccc(O)c(C(=O)Nc2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.63
HDAC1 Q13547 2/20 0.63
HDAC2 Q92769 2/20 0.63
HDAC10 Q969S8 2/20 0.63
HDAC11 Q96DB2 2/20 0.63
HDAC8 Q9BY41 2/20 0.63
HDAC6 Q9UBN7 2/20 0.63
EGFR P00533 1/20 0.63
HDAC4 P56524 1/20 0.63
HDAC7 Q8WUI4 1/20 0.63
HDAC9 Q9UKV0 1/20 0.63
HDAC5 Q9UQL6 1/20 0.63
P2RX1 P51575 4/20 0.58
TMPRSS4 Q9NRS4 2/20 0.58
SLC2A1 P11166 1/20 0.58
P2RX4 Q99571 1/20 0.58
P2RX7 Q99572 1/20 0.58
RXFP1 Q9HBX9 7/20 0.57
CNR2 P34972 1/20 0.49
MAPT P10636 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30288530 1.00 HDAC3 (0.63) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL29372818 1.00 HDAC3 (0.63) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL29781391 0.82 P2RX1 (0.56) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL14582017 0.82 P2RX1 (0.56) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL10607741 0.81 P2RX1 (0.63) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL10347262 0.80 P2RX1 (0.56) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL17134082 0.78 HDAC3 (0.58) HDAC3HDAC1HDAC2MAPTMEN1
Salfluverine SCHEMBL1552202 0.78 P2RX1 (0.69) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL31129776 0.78 HDAC3 (0.78) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL17817420 0.78 HDAC3 (0.78) HDAC3HDAC1HDAC2HDAC10HDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2313026-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS Castle Beach, L.L.C. (US) 2011-04-27 EP claimed
EP-2209472-A1 USE OF NITRIC OXIDE TO ENHANCE THE EFFICACY OF SILVER AND OTHER TOPICAL WOUND CARE AGENTS The University of North Carolina at Chapel Hill (US) 2010-07-28 EP claimed
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS Castle Beach, LLC (US) 2010-02-18 US claimed
WO-2010019680-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS HOMOLA ANDREW M (US) 2010-02-18 WO claimed
WO-2009049208-A1 USE OF NITRIC OXIDE TO ENHANCE THE EFFICACY OF SILVER AND OTHER TOPICAL WOUND CARE AGENTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2009-04-16 WO claimed
EP-0805672-B1 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA ANDREW M (US) 2004-08-25 EP claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
EP-0628302-A2 Oral composition containing salicylanilide antibacterial agent Colgate-Palmolive Company (US) 1994-12-14 EP claimed
US-5275805-A Inhibitors of plaque in mouths with mixtures of salicylanilide and nonionic surfactants COLGATE-PALMOLIVE CO. 1994-01-04 US claimed
EP-3528776-B1 REDUCED-ETHANOL MOUTH RINSE FORMULATIONS KENVUE BRANDS LLC (US) 2025-11-26 EP disclosed
EP-4088716-B1 AN ORAL TABLET FOR INDUCED SALIVA GENERATION FERTIN PHARMA AS (DK) 2024-10-16 EP disclosed
WO-2024008261-A1 CANNABINOID LIPID PREMIXTURE FERTIN PHARMA A/S (DK) 2024-01-11 WO disclosed
US-11857653-B2 Method of providing an oral care benefit using a poorly-soluble calcium compound and fluoride JOHNSON & JOHNSON CONSUMER INC. (US) 2024-01-02 US disclosed
EP-3787604-B1 A TABLETED CHEWING GUM SUITABLE FOR ACTIVE PHARMACEUTICAL INGREDIENTS FERTIN PHARMA AS (DK) 2023-07-05 EP disclosed
EP-0223515-A2 Oral compositions comprising salicylamides and zinc salts for the synergistic inhibition of dental plaque UNILEVER PLC (GB) 1987-05-27 EP disclosed
US-4659826-A Synthesis of salicylamides with improved yield and purity LEVER BROTHERS COMPANY (US) 1987-04-21 US disclosed
US-4656031-A SURFACTANT, ABRASIVE AND ANTI-PLAQUE AGENT LEVER BROTHERS COMPANY (US) 1987-04-07 US disclosed
EP-0161898-A2 Dentifrice compositions UNILEVER PLC (GB) 1985-11-21 EP disclosed
EP-0144204-A2 Process for preparing salicylamide compounds UNILEVER PLC (GB) 1985-06-12 EP disclosed
EP-0143628-A2 Process for preparing salicylamide compounds UNILEVER PLC (GB) 1985-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS LIPA, MMP7, CTSA HDAC3 1596/4885HDAC1 1347/4885HDAC2 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.