Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 5/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347439 | 1.00 | HPGD (0.34) | HPGDALDH1A1F2GLAACACB | |
| SCHEMBL10347437 | 1.00 | HPGD (0.34) | HPGDALDH1A1F2GLAACACB | |
| SCHEMBL10347410 | 0.93 | TLR4 (0.36) | HPGDALDH1A1F2GLAACACB | |
| SCHEMBL10347409 | 0.93 | TLR4 (0.36) | HPGDALDH1A1F2GLAACACB | |
| SCHEMBL10347412 | 0.93 | TLR4 (0.36) | HPGDALDH1A1F2GLAACACB | |
| SCHEMBL10347522 | 0.89 | KMT2A (0.36) | ACACBACACAHCRTR1HCRTR2DGAT1 | |
| SCHEMBL10347524 | 0.89 | KMT2A (0.36) | ACACBACACAHCRTR1HCRTR2DGAT1 | |
| SCHEMBL10347523 | 0.89 | KMT2A (0.36) | ACACBACACAHCRTR1HCRTR2DGAT1 | |
| SCHEMBL10347399 | 0.87 | KMT2A (0.36) | HPGDALDH1A1GLAACACBACACA | |
| SCHEMBL10347400 | 0.87 | KMT2A (0.36) | HPGDALDH1A1GLAACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365641-A1 | PYRIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989010356-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-02 | — | — | WO | disclosed |