SCHEMBL10347443

SCHEMBL10347443

[CH2]C(CCCCCCC)CCC(C)C

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.42
SPHK1 Q9NYA1 1/20 0.40
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
PLA2G1B P04054 1/20 0.38
PLA2G2A P14555 1/20 0.38
ACE2 Q9BYF1 1/20 0.36
GPR84 Q9NQS5 3/20 0.35
FDPS P14324 3/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16105085 0.93 OPRM1 (0.44) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL28495374 0.93 OPRM1 (0.44) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL5090094 0.93 OPRM1 (0.44) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL17183473 0.93 OPRM1 (0.44) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL5090681 0.93 OPRM1 (0.44) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL9137626 0.93 OPRM1 (0.44) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL10347304 0.90 OPRM1 (0.46) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL10611346 0.90 DNM1 (0.36) OPRM1LMNADNM1TSHRFDPS
SCHEMBL22129681 0.87 TSHR (0.50) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL198850 0.87 TSHR (0.50) OPRM1SPHK1LMNADNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0162891-B1 MIXTURE OF AMINES AND PROCESS FOR PRODUCING IT MONSANTO COMPANY (US) 1990-05-23 EP claimed
EP-0162891-A4 Mixture of amines and process for producing it. MONSANTO CO (US) 1987-03-12 EP claimed
EP-0162891-A1 Mixture of amines and process for producing it. MONSANTO CO (US) 1985-12-04 EP claimed
WO-1985002173-A1 NEW ROUTE TO LONG CHAIN AMINES MONSANTO COMPANY (US) 1985-05-23 WO claimed