SCHEMBL10347482

SCHEMBL10347482

CCCCCCCCS(=O)(=O)c1ccc(O)c(C(=O)Nc2ccc([N+](=O)[O-])cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.53
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
NPC1 O15118 1/20 0.53
HSP90AA1 P07900 1/20 0.53
PKM P14618 1/20 0.53
PAX8 Q06710 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
LMNA P02545 5/20 0.52
HTT P42858 2/20 0.52
F10 P00742 1/20 0.49
PLAU P00749 1/20 0.49
PLAT P00750 1/20 0.49
CA12 O43570 2/20 0.47
CA9 Q16790 2/20 0.47
ALOX12 P18054 1/20 0.46
P2RX1 P51575 3/20 0.45
TMPRSS4 Q9NRS4 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10347139 1.00 MAPT (0.53) MAPTKMT2AMEN1NPC1HSP90AA1
SCHEMBL10347602 0.86 ALOX15 (0.46) MAPTKMT2AMEN1LMNAHTT
SCHEMBL10347261 0.86 ALOX15 (0.46) MAPTKMT2AMEN1LMNAHTT
SCHEMBL10347601 0.86 ALOX15 (0.46) MAPTKMT2AMEN1LMNAHTT
SCHEMBL10606316 0.84 MAPT (0.56) MAPTKMT2AMEN1NPC1HSP90AA1
SCHEMBL10347260 0.83 P2RX1 (0.54) MAPTKMT2AMEN1LMNACA12
SCHEMBL10347520 0.83 P2RX1 (0.54) MAPTKMT2AMEN1LMNACA12
SCHEMBL10385047 0.82 MAPT (0.61) MAPTKMT2AMEN1NPC1HSP90AA1
SCHEMBL9067530 0.80 F10 (0.55) MAPTKMT2AMEN1NPC1HSP90AA1
SCHEMBL10347262 0.77 P2RX1 (0.56) MAPTKMT2AMEN1NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4939132-A Novel 5-alkylsulfonylsalicylanilides and microbiocidal compositions for controlling the growth of microorganisms THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-07-03 US disclosed
EP-0198366-B1 NOVEL 5-ALKYLSULFONYLSALICYLANLIDES AND MICROBIOCIDAL COMPOSITIONS FOR CONTROLLING THE GROWTH OF MICROORGANISMS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-05-09 EP disclosed
EP-0198366-A1 Novel 5-alkylsulfonylsalicylanlides and microbiocidal compositions for controlling the growth of microorganisms THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1986-10-22 EP disclosed