Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL14918 | 0.91 | MAP3K14 (0.44) | CRBNMAP3K14MEN1APEX1KMT2A | |
| Oxalic Acid SCHEMBL9728854 | 0.89 | MAP3K14 (0.43) | CRBNMAP3K14MEN1APEX1KMT2A | |
| SCHEMBL15494454 | 0.89 | — | — | |
| Methacrylic Acid SCHEMBL2861566 | 0.88 | MAP3K14 (0.36) | CRBNMAP3K14MEN1APEX1KMT2A | |
| SCHEMBL7530545 | 0.87 | MAP3K14 (0.41) | CRBNMAP3K14MEN1APEX1KMT2A | |
| Ammonia Solution, Strong SCHEMBL25176856 | 0.86 | — | — | |
| SCHEMBL320576 | 0.86 | — | — | |
| Phosphine SCHEMBL22345181 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3986242 | 0.86 | — | — | |
| SCHEMBL31244467 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114438048-B | Urate oxidase preparation and application thereof | 重庆派金生物科技有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118497161-A | Polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117866929-A | Pegylated arginine deiminase dimer preparation and use thereof | 重庆派金生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-114438048-A | Urate oxidase preparation and application thereof | 重庆派金生物科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-111909906-A | Urate oxidase modified by polyethylene glycol | 重庆派金生物科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| EP-1370295-A2 | NEUTRAL AND ANIONIC COLLOIDAL PARTICLES FOR GENE DELIVERY | GENCELL S.A. (FR) | 2003-12-17 | — | — | EP | claimed |
| WO-2002043769-A2 | NEUTRAL AND ANIONIC COLLOIDAL PARTICLES FOR GENE DELIVERY | GENCELL S.A. (FR) | 2002-06-06 | — | — | WO | claimed |
| CN-114438048-B | Urate oxidase preparation and application thereof | 重庆派金生物科技有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118497161-A | Polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-111909906-B | Polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117866929-A | Pegylated arginine deiminase dimer preparation and use thereof | 重庆派金生物科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-109890845-B | anti-RANKL antibodies and uses thereof | 伊莱利利公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114438048-A | Urate oxidase preparation and application thereof | 重庆派金生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-1370571-A2 | METHODS AND APPARATUS FOR GEL-FREE QUALITATIVE AND QUANTITATIVE PROTEOME ANALYSIS, AND USES THEREFOR | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. (BE) | 2003-12-17 | — | — | EP | disclosed |
| CN-1115563-C | Acylated protein aggregates and their use to reduce interference in immunoassays | ROCHE DIAGNOSTICS GMBH (DE) | 2003-07-23 | — | — | CN | disclosed |
| WO-2002077016-A2 | METHODS AND APPARATUS FOR GEL-FREE QUALITATIVE AND QUANTITATIVE PROTEOME ANALYSIS, AND USES THEREFORE | VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) | 2002-10-03 | — | — | WO | disclosed |
| EP-0930895-A1 | PREPARATION OF PROTEIN/POLYSACCHARIDE CONJUGATE VACCINES USING HOMOBIFUNCTIONAL AND HETEROBIFUNCTIONAL VINYLSULFONES | Virion Systems, Inc. (US) | 1999-07-28 | — | — | EP | disclosed |
| WO-1997041897-A1 | PREPARATION OF PROTEIN/POLYSACCHARIDE CONJUGATE VACCINES USING HOMOBIFUNCTIONAL AND HETEROBIFUNCTIONAL VINYLSULFONES | VIRION SYSTEMS, INC. (US) | 1997-11-13 | — | — | WO | disclosed |
| CN-1120864-A | Acylated protein aggregates and their use in suppressing interference in immunoassays | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-17 | — | — | CN | disclosed |
| WO-1996006624-A1 | A MUTANT PROTEIN AND METHODS AND MATERIALS FOR MAKING AND USING IT | IMMTECH INTERNATIONAL, INC. (US) | 1996-03-07 | — | — | WO | disclosed |