Methacrylic Acid

Methacrylic Acid

SCHEMBL2861566

C=C(C)C(=O)O.O=C1CC(O)C(=O)N1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.36
CRBN Q96SW2 3/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.32
APEX1 P27695 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DDB1 Q16531 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28059035 0.98 MAP3K14 (0.35) MAP3K14CRBNALDH1A1LMNAMEN1
Acetic Acid SCHEMBL1034775 0.88 CRBN (0.44) MAP3K14CRBNALDH1A1LMNAMEN1
Acetone SCHEMBL28868967 0.86 MAP3K14 (0.43) MAP3K14CRBNALDH1A1LMNAMEN1
Bicarbonate SCHEMBL14918 0.84 MAP3K14 (0.44) MAP3K14CRBNALDH1A1MEN1APEX1
Ethane SCHEMBL28857929 0.82 MAP3K14 (0.46) MAP3K14CRBNALDH1A1LMNAMEN1
SCHEMBL11288 0.82
Carbamic Acid SCHEMBL2782197 0.80 MEN1 (0.42) MAP3K14CRBNALDH1A1MEN1APEX1
SCHEMBL7530545 0.80 MAP3K14 (0.41) MAP3K14CRBNALDH1A1MEN1APEX1
Ammonia Solution, Strong SCHEMBL25176856 0.80
SCHEMBL320576 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021063538-A1 DECARBOXYLATION OF N-OXYPHTHALIMIDE-BASED POLYMERS Karlsruher Institut für Technologie (DE) 2021-04-08 WO disclosed
EP-3504188-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS Chelation Partners Incorporated (CA) 2019-07-03 EP disclosed
WO-2018035613-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS CHELATION PARTNERS INCORPORATED (CA) 2018-03-01 WO disclosed
WO-2015160793-A1 BIODEGRADABLE, THERMALLY RESPONSIVE INJECTABLE HYDROGEL FOR TREATMENT OF ISCHEMIC CARDIOMYOPATHY UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2015-10-22 WO disclosed
WO-2010127254-A2 THERMORESPONSIVE, BIODEGRADABLE, ELASTOMERIC MATERIAL AND USES THEREFOR UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2010-11-04 WO disclosed
EP-2038320-A4 PARTICLES CONTAINING MULTI- BLOCK POLYMERS INVITROGEN DYNAL AS (NO) 2009-07-08 EP disclosed
EP-2038320-A1 PARTICLES CONTAINING MULTI- BLOCK POLYMERS Invitrogen Dynal AS (NO) 2009-03-25 EP disclosed
WO-2008003099-A1 PARTICLES CONTAINING MULTI- BLOCK POLYMERS INVITROGEN, DYNAL AS (NO) 2008-01-03 WO disclosed