Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | GJB2 | P29033 | 1/20 | 0.36 |
| ▸ | GJA1 | P17302 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347983 | 0.85 | KDM4E (0.39) | IDO1AGXTTACR1MAPTKDM4E | |
| SCHEMBL18542478 | 0.85 | KCNA5 (0.42) | TACR1MAPTKDM4EKCNA5 | |
| SCHEMBL18542482 | 0.85 | KCNA5 (0.42) | TACR1MAPTKDM4EKCNA5 | |
| SCHEMBL24597253 | 0.76 | IDO1 (0.50) | RENIDO1AGXTNAAAKCNA5 | |
| SCHEMBL18542512 | 0.76 | BCHE (0.39) | MAPT | |
| SCHEMBL18542513 | 0.76 | BCHE (0.39) | MAPT | |
| SCHEMBL17898753 | 0.74 | IDO1 (0.42) | IDO1AGXTTACR1MAPTKDM4E | |
| SCHEMBL18542441 | 0.74 | ALOX5 (0.43) | RENMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL18542440 | 0.74 | ALOX5 (0.43) | RENMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL17005591 | 0.73 | IDO1 (0.41) | IDO1AGXTTACR1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962146-A | 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives | SCHERING CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0362267-A1 | 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES | SCHERING CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988008426-A1 | 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES | SCHERING CORPORATION (US) | 1988-11-03 | — | — | WO | disclosed |