Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 1/20 | 0.39 |
| ▸ | GJA1 | P17302 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348013 | 0.85 | REN (0.39) | KDM4EMAPTGJB2GJA1TACR1 | |
| SCHEMBL16154920 | 0.80 | KDM4E (0.37) | KDM4EMAPTGJB2GJA1TACR1 | |
| SCHEMBL17898753 | 0.79 | IDO1 (0.42) | KDM4EMAPTGJB2GJA1TACR1 | |
| SCHEMBL15937685 | 0.78 | IDO1 (0.41) | KDM4EMAPTGJB2GJA1TACR1 | |
| SCHEMBL8006235 | 0.75 | SLC5A1 (0.42) | MAPTGJB2GJA1TACR1IDO1 | |
| SCHEMBL8006236 | 0.75 | SLC5A1 (0.42) | MAPTGJB2GJA1TACR1IDO1 | |
| SCHEMBL8008165 | 0.75 | SLC5A1 (0.42) | MAPTGJB2GJA1TACR1IDO1 | |
| SCHEMBL8398372 | 0.75 | LGALS8 (0.42) | GJB2GJA1TACR1IDO1AGXT | |
| SCHEMBL13380987 | 0.74 | NPC1 (0.45) | SLC5A2SLC5A1 | |
| SCHEMBL15953973 | 0.73 | IDO1 (0.52) | TACR1IDO1AGXTNAAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962146-A | 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives | SCHERING CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0362267-A1 | 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES | SCHERING CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988008426-A1 | 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES | SCHERING CORPORATION (US) | 1988-11-03 | — | — | WO | disclosed |