Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25300424 | 0.86 | ALDH1A1 (0.40) | PKMHIF1AMAPK1TSHRALDH1A1 | |
| SCHEMBL10347988 | 0.83 | PHOSPHO1 (0.43) | HIF1ATSHRALDH1A1HPGDGABRA2 | |
| SCHEMBL10632971 | 0.81 | TDP1 (0.42) | HIF1AALDH1A1TDP1MAPTNOTUM | |
| SCHEMBL10718846 | 0.80 | ALDH1A1 (0.43) | HIF1AMAPK1TSHRALDH1A1GABRA2 | |
| SCHEMBL22518629 | 0.78 | MGAM (0.53) | PKMHIF1AALDH1A1TDP1MAPT | |
| SCHEMBL18153033 | 0.78 | HSD17B10 (0.47) | MAPK1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL11487178 | 0.78 | CHRM1 (0.50) | HIF1AALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL26260329 | 0.77 | MAPT (0.48) | MAPK1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL31039845 | 0.74 | F2 (0.43) | PKMTSHRALDH1A1HPGDTDP1 | |
| SCHEMBL10582824 | 0.73 | MGAM (0.36) | HIF1ATSHRALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200872-B1 | HERBICIDAL AND INSECTICIDAL AGENT BASED ON PYRAZOL DERIVATIVES | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |
| US-4746354-A | PRE- AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-24 | — | — | US | disclosed |
| EP-0200872-A1 | Herbicidal and insecticidal agent based on pyrazol derivatives | BAYER AG (DE) | 1986-11-12 | — | — | EP | disclosed |