Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488823 | 0.83 | PTGS1 (0.56) | CHRM1PTGS1AKR1C3AKR1C2KMT2A | |
| Hydrochloric Acid SCHEMBL11493900 | 0.82 | PTGS1 (0.55) | CHRM1PTGS1AKR1C3AKR1C2KMT2A | |
| SCHEMBL11493818 | 0.81 | PTGS1 (0.54) | CHRM1PTGS1AKR1C3AKR1C2KMT2A | |
| SCHEMBL11487149 | 0.81 | PTGS1 (0.57) | CHRM1PTGS1AKR1C3AKR1C2KMT2A | |
| SCHEMBL10348148 | 0.78 | PKM (0.49) | ALDH1A1HIF1ASMN1; SMN2F2PLAU | |
| Piperazine SCHEMBL11487580 | 0.77 | PTGS1 (0.53) | CHRM1PTGS1AKR1C3AKR1C2KMT2A | |
| SCHEMBL11485527 | 0.76 | PTGS1 (0.51) | CHRM1PTGS1AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL11493481 | 0.74 | CHRM1 (0.45) | CHRM1PTGS1PLAUELANE | |
| SCHEMBL11486961 | 0.74 | PTGS1 (0.42) | CHRM1PTGS1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11493771 | 0.74 | PTGS1 (0.42) | CHRM1PTGS1LMNAPLAUELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |