SCHEMBL10348153

SCHEMBL10348153

CCCCN(CCCCS(=O)(=O)O)c1ccccc1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 5/20 0.35
HSD17B10 Q99714 2/20 0.35
ESR1 P03372 1/20 0.35
ELANE P08246 1/20 0.34
S1PR2 O95136 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GFER P55789 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 3/20 0.33
CNR2 P34972 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1324109 0.83 CYP1A2 (0.44) TDP1ALDH1A1HSD17B10ELANEMEN1
SCHEMBL2229681 0.82 CYP1A2 (0.43) ALDH1A1HSD17B10TP53KDM4ECNR2
Hydrochloric Acid SCHEMBL4663787 0.82 CYP1A2 (0.43) TDP1ALDH1A1HSD17B10ELANEMEN1
SCHEMBL9014379 0.80 CYP1A2 (0.42) ALDH1A1HSD17B10TP53KDM4ECNR2
SCHEMBL5167109 0.77 ALDH1A1 (0.43) TDP1ALDH1A1S1PR2S1PR1S1PR3
SCHEMBL25453791 0.77 CYP1A2 (0.42) TDP1ALDH1A1HSD17B10ELANEHPGD
SCHEMBL6302960 0.75 ESR1 (0.48) TDP1ALDH1A1ESR1ELANEHPGD
SCHEMBL11081053 0.75 S100B (0.50) ALDH1A1ESR1MEN1KMT2AKDM4E
SCHEMBL21286204 0.74 CNR2 (0.34) ALDH1A1ESR1ELANEHPGDMEN1
Sulfuric Acid SCHEMBL1304808 0.74 HSD17B10 (0.39) TDP1ALDH1A1HSD17B10ESR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0184057-B1 COLOUR-PHOTOGRAPHIC MATERIAL CONTAINING A COUPLER Agfa-Gevaert AG (DE) 1990-04-11 EP disclosed
EP-0079540-B1 HAIR DYEING COMPOSITIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1985-03-20 EP disclosed
EP-0128272-A1 2,4-Diaminobenzene derivates, their production and use as coupling substances Henkel Kommanditgesellschaft auf Aktien (DE) 1984-12-19 EP disclosed
EP-0118071-A2 Photographic developer Agfa-Gevaert AG (DE) 1984-09-12 EP disclosed
EP-0043037-A1 Dispersion process Agfa-Gevaert AG (DE) 1982-01-06 EP disclosed
EP-0039034-A1 Coupling components for the oxidative dyeing of hair and their use, as well as compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1981-11-04 EP disclosed
US-4226595-A Oxidation hair-coloring preparation based upon N,N-bis-(β-hydroxyethyl)-m-phenylenediamines HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1980-10-07 US disclosed