Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 12/20 | 0.41 |
| ▸ | DRD4 | P21917 | 12/20 | 0.41 |
| ▸ | DRD3 | P35462 | 12/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102932 | 0.88 | DRD2 (0.47) | MEN1GAAKMT2ADRD2DRD4 | |
| SCHEMBL102930 | 0.88 | DRD2 (0.47) | MEN1GAAKMT2ADRD2DRD4 | |
| SCHEMBL103640 | 0.87 | MEN1 (0.47) | MEN1GAAKMT2ADRD2DRD4 | |
| SCHEMBL103639 | 0.87 | MEN1 (0.47) | MEN1GAAKMT2ADRD2DRD4 | |
| SCHEMBL106059 | 0.79 | L3MBTL1 (0.37) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL106060 | 0.79 | L3MBTL1 (0.37) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL103214 | 0.79 | PRMT1 (0.38) | DRD2PRMT1MAPT | |
| SCHEMBL103212 | 0.79 | PRMT1 (0.38) | DRD2PRMT1MAPT | |
| SCHEMBL102207 | 0.77 | MEN1 (0.47) | MEN1GAAKMT2ADRD2DRD4 | |
| SCHEMBL102543 | 0.77 | MEN1 (0.47) | MEN1GAAKMT2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |