Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011328 | 0.88 | POLB (0.56) | PARP1SMN1; SMN2HPGDALDH1A1MEN1 | |
| Valine SCHEMBL10944604 | 0.87 | SMN1; SMN2 (0.44) | PARP1SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL30502814 | 0.86 | NLRP3 (0.56) | SMN1; SMN2LMNAALDH1A1SCN3AMEN1 | |
| SCHEMBL5941054 | 0.86 | NLRP3 (0.56) | SMN1; SMN2LMNAALDH1A1SCN3AMEN1 | |
| SCHEMBL10668835 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL307790 | 0.84 | MEN1 (0.62) | SMN1; SMN2HPGDLMNAALDH1A1SCN3A | |
| SCHEMBL7224255 | 0.82 | SCN3A (0.49) | SMN1; SMN2LMNAALDH1A1SCN3AMEN1 | |
| SCHEMBL10797916 | 0.82 | L3MBTL1 (0.46) | PARP1SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL7219478 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAALDH1A1SCN3AMEN1 | |
| SCHEMBL7223995 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAALDH1A1SCN3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4493755-A | Electrolytic preparation of orthoalkyl-2-halo-N-acylanilides | MONSANTO COMPANY (US) | 1985-01-15 | — | — | US | claimed |
| EP-0185128-B1 | CATALYTIC HYDRODESULFURIZATION OF ORTHO-AMINOBENZYL SULFIDES | Monsanto Company (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4806687-A | Catalytic hydrodesulfurization of ortho-aminobenzylsulfides | MONSANTO COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| US-4731109-A | Herbicidal 2-haloacetanilides | MONSANTO COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| US-4618713-A | Preparation of 2'-methyl-2-haloacetanilides | MONSANTO COMPANY (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0185128-A1 | Catalytic hydrodesulfurization of ortho-aminobenzyl sulfides | Monsanto Company (US) | 1986-06-25 | — | — | EP | disclosed |
| US-4578514-A | Synthesis of sulfilimines | MONSANTO COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| US-4493755-A | Electrolytic preparation of orthoalkyl-2-halo-N-acylanilides | MONSANTO COMPANY (US) | 1985-01-15 | — | — | US | disclosed |
| US-4404069-A | Electrolytic desulfurization of anilino sulfur compounds | MONSANTO COMPANY (US) | 1983-09-13 | — | — | US | disclosed |