SCHEMBL10349031

SCHEMBL10349031

CCCCCCCCC(=O)Nc1cccc(-n2nnnc2S)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
POLB P06746 1/20 0.48
HDAC3 O15379 5/20 0.47
HDAC1 Q13547 5/20 0.47
HDAC2 Q92769 5/20 0.47
HDAC10 Q969S8 5/20 0.47
HDAC8 Q9BY41 5/20 0.47
HDAC6 Q9UBN7 5/20 0.47
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
SOAT2 O75908 3/20 0.46
SOAT1 P35610 3/20 0.46
ALDH1A1 P00352 2/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
MAPT P10636 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
USP2 O75604 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6571817 1.00 LMNA (0.48) LMNAPOLBHDAC3HDAC1HDAC2
SCHEMBL7303949 1.00 LMNA (0.48) LMNAPOLBHDAC3HDAC1HDAC2
SCHEMBL9769971 1.00 LMNA (0.48) LMNAPOLBHDAC3HDAC1HDAC2
SCHEMBL8059281 1.00 LMNA (0.48) LMNAPOLBHDAC3HDAC1HDAC2
SCHEMBL14498627 1.00 LMNA (0.48) LMNAPOLBHDAC3HDAC1HDAC2
SCHEMBL9769968 1.00 LMNA (0.48) LMNAPOLBHDAC3HDAC1HDAC2
SCHEMBL5154079 0.99 LMNA (0.47) LMNAPOLBHDAC3HDAC1HDAC2
SCHEMBL14498628 0.96 SMN1; SMN2 (0.49) LMNAHDAC3HDAC1HDAC2HDAC10
SCHEMBL9769965 0.91 ALDH1A1 (0.48) LMNARAB9AALDH1A1CRHBPCRHR2
SCHEMBL10468788 0.87 LMNA (0.48) LMNAPOLBHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0175148-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1990-07-25 EP disclosed
US-4770991-A HIGH SPEED GIVING HIGH CONTRAST AND HIGH MAXIMUM DENSITY IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
US-4657847-A HIGH SPEED, CONTRAST AND DENSITY; ANTIFOGGING AGENTS; ANTISOILANTS FUJI PHOTO FILM CO., LTD. (JP) 1987-04-14 US disclosed
EP-0175148-A2 Silver halide photographic light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1986-03-26 EP disclosed