Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10382897 | 0.99 | GSK3B (0.45) | GSK3BCCR2KCNH2KDM1ARCOR1 | |
| SCHEMBL10382643 | 0.82 | GSK3B (0.46) | GSK3BKDM1ARCOR1 | |
| SCHEMBL24005868 | 0.82 | DRD2 (0.37) | GSK3B | |
| SCHEMBL10349839 | 0.82 | GSK3B (0.47) | GSK3BKDM1ARCOR1KMT2A | |
| SCHEMBL31449823 | 0.82 | GSK3B (0.39) | GSK3BKDM1A | |
| SCHEMBL30368129 | 0.80 | GSK3B (0.48) | GSK3B | |
| SCHEMBL18947216 | 0.80 | EPHX2 (0.43) | GSK3BKMT2ABIRC2 | |
| SCHEMBL7013419 | 0.78 | GSK3B (0.42) | GSK3B | |
| SCHEMBL31444433 | 0.77 | GSK3B (0.43) | GSK3BCCR2 | |
| SCHEMBL27948360 | 0.75 | GSK3B (0.44) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211746-B1 | PHENYL-PIPERAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THERAPEUTICAL USE | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1990-05-23 | — | — | EP | claimed |
| US-4912110-A | Antidepressive substituted phenylpiperazine compounds | LABORATOIRE L. LAFTON (FR) | 1990-03-27 | — | — | US | claimed |
| EP-0211746-A1 | Phenyl-piperazine derivatives, process for their preparation and therapeutical use | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-02-25 | — | — | EP | claimed |
| EP-0211746-B1 | PHENYL-PIPERAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THERAPEUTICAL USE | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1990-05-23 | — | — | EP | disclosed |
| US-4912110-A | Antidepressive substituted phenylpiperazine compounds | LABORATOIRE L. LAFTON (FR) | 1990-03-27 | — | — | US | disclosed |
| EP-0211746-A1 | Phenyl-piperazine derivatives, process for their preparation and therapeutical use | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-02-25 | — | — | EP | disclosed |