Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19049065 | 0.82 | HTR2C (0.39) | GSK3BSLC6A3SMN1; SMN2HTR2C | |
| SCHEMBL10388908 | 0.79 | KDM4E (0.44) | GSK3B | |
| SCHEMBL30368129 | 0.78 | GSK3B (0.48) | GSK3BHTR6 | |
| SCHEMBL27520764 | 0.77 | GSK3B (0.43) | GSK3BRAB9AHTR6SLC6A3 | |
| SCHEMBL19049080 | 0.75 | GSK3B (0.44) | GSK3BRAB9A | |
| SCHEMBL31444433 | 0.75 | GSK3B (0.43) | GSK3BHTR6TP53HTR2AHTR2C | |
| SCHEMBL10349658 | 0.75 | GSK3B (0.46) | GSK3B | |
| Hydrochloric Acid SCHEMBL10382897 | 0.74 | GSK3B (0.45) | GSK3BHTR2AHTR2CHTR2B | |
| SCHEMBL18997546 | 0.72 | GSK3B (0.42) | GSK3B | |
| SCHEMBL18947216 | 0.72 | EPHX2 (0.43) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101878217-B | Agent for prevention and/or treatment of skin diseases | KYOWA HAKKO KIRIN CO LTD | 2014-01-15 | — | — | CN | disclosed |