SCHEMBL10349727

SCHEMBL10349727

CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccccc2Oc2ccccc2C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.49
TSHR P16473 4/20 0.42
KDM4E B2RXH2 2/20 0.42
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
MAPK1 P28482 2/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
PHLPP2 Q6ZVD8 1/20 0.41
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
NQO1 P15559 1/20 0.40
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX15 P16050 1/20 0.39
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6559034 0.89 SLC2A1 (0.58) SLC2A1TSHRKDM4ETP53TDP1
SCHEMBL14594214 0.83 SLC2A1 (0.51) SLC2A1TSHRKDM4ETP53TDP1
SCHEMBL21420998 0.78 IDO1 (0.41) TSHRTDP1KMT2AALDH1A1HTR2A
SCHEMBL3893906 0.78 SLC2A1 (0.47) SLC2A1TSHRKDM4ETP53TDP1
SCHEMBL13649911 0.76 SLC2A1 (0.46) SLC2A1TSHRKDM4ETP53TDP1
SCHEMBL6558649 0.76 SLC2A1 (0.46) SLC2A1TSHRKDM4ETDP1MAPK1
SCHEMBL2391501 0.76 SLC2A1 (0.46) SLC2A1TSHRKDM4ETDP1MAPK1
SCHEMBL6558634 0.76 SLC2A1 (0.46) SLC2A1TSHRKDM4ETP53TDP1
SCHEMBL6557998 0.76 SLC2A1 (0.46) SLC2A1TSHRKDM4ETDP1MAPK1
SCHEMBL7110610 0.74 SLC2A1 (0.61) SLC2A1TSHRKDM4ETDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0196484-B1 PRESSURE SENSITIVE MANIFOLD SHEET KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1990-05-09 EP disclosed
US-4704379-A Pressure sensitive manifold sheet KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-11-03 US disclosed
EP-0196484-A1 Pressure sensitive manifold sheet KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1986-10-08 EP disclosed