Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594214 | 0.94 | SLC2A1 (0.51) | SLC2A1TSHRTP53KDM4EMEN1 | |
| SCHEMBL10349727 | 0.89 | SLC2A1 (0.49) | SLC2A1TSHRTP53KDM4EMEN1 | |
| SCHEMBL9559182 | 0.84 | SLC2A1 (0.61) | SLC2A1TSHRTP53KDM4EMEN1 | |
| SCHEMBL12955609 | 0.81 | KDM4E (0.44) | SLC2A1TSHRTP53KDM4EMEN1 | |
| SCHEMBL3039320 | 0.81 | IDO1 (0.58) | TSHRTP53MEN1KMT2ACA12 | |
| SCHEMBL9658333 | 0.80 | SLC2A1 (0.65) | SLC2A1TSHRTP53KDM4EMEN1 | |
| SCHEMBL29139801 | 0.80 | SLC2A1 (0.44) | SLC2A1TSHRTP53KDM4EMEN1 | |
| SCHEMBL10689340 | 0.80 | TP53 (0.42) | SLC2A1TSHRTP53KDM4EMEN1 | |
| SCHEMBL10489556 | 0.78 | SLC2A1 (0.49) | SLC2A1TSHRTP53KDM4EMEN1 | |
| SCHEMBL31409217 | 0.78 | ALDH1A1 (0.47) | TSHRTP53CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | claimed |
| US-6166013-A | Glucocortiocoid-selective agents | ABBOTT LABORATORIES (US) | 2000-12-26 | — | — | US | disclosed |