SCHEMBL2391501

SCHEMBL2391501

CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccccc2F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.46
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TSHR P16473 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
MAPT P10636 3/20 0.42
MAPK1 P28482 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KCNH2 Q12809 2/20 0.42
MAT2A P31153 1/20 0.42
CYP1A2 P05177 1/20 0.42
PHLPP2 Q6ZVD8 1/20 0.42
ALDH1A1 P00352 10/20 0.42
LMNA P02545 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14594215 0.93 ALDH1A1 (0.48) SLC2A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL3893906 0.79 SLC2A1 (0.47) SLC2A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL7541462 0.79 KCNH2 (0.47) SLC2A1KMT2ACYP3A4TSHRTDP1
SCHEMBL30327039 0.78 KMT2A (0.43) SLC2A1MEN1KMT2ACYP3A4TSHR
SCHEMBL13649911 0.78 SLC2A1 (0.46) SLC2A1MEN1KMT2ACYP3A4TSHR
SCHEMBL6557998 0.78 SLC2A1 (0.46) SLC2A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL6558634 0.78 SLC2A1 (0.46) SLC2A1MEN1KMT2ACYP3A4TSHR
SCHEMBL6558649 0.78 SLC2A1 (0.46) SLC2A1MEN1KMT2ACYP3A4TSHR
SCHEMBL41457 0.78 IDO1 (0.53) KMT2ATSHRTDP1ALDH1A1GAA
SCHEMBL8048442 0.77 SLC2A1 (0.42) SLC2A1CYP3A4TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1100483-B1 GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS ABBOTT LAB (US) 2004-09-29 EP claimed
US-8524438-B2 Etch resist solution, method of fabricating thin film pattern using the same and method of fabricating an LCD device using the same LG DISPLAY CO., LTD. (KR) 2013-09-03 US disclosed
US-8012652-B2 Method of forming a thin film pattern and method of fabricating a liquid crystal display device LG DISPLAY CO., LTD. (KR) 2011-09-06 US disclosed
US-20080264902-A1 Method of forming a thin film pattern and method of fabricating a liquid crystal display device LG ELECTRONICS INC. (KR) 2008-10-30 US disclosed
US-20080173615-A1 Etch resist solution, method of fabricating thin film pattern using the same and method of fabricating an LCD device using the same LG DISPLAY CO., LTD. (KR) 2008-07-24 US disclosed
US-6479217-B1 PHOTOSENSITIVE RECORDING; APPLYING ACTINIC RADIATION; PHOTOPOLYMERIZATION SPECTRA GROUP LIMITED, INC. 2002-11-12 US disclosed
US-20020160310-A1 Method for producing selectively colorable printing plates SPECTRA GROUP LIMITED, INC. 2002-10-31 US disclosed
US-6433035-B1 LEUCO DYE OR DI-, TRI- OR MONOARYLMETHANE DYE COLOR FORMERS YIELD CATIONIC DYE WHEN EXPOSED TO ACTINIC RADIATION IN PRESENCE OF OXIDIZER; BLEACHING AT HIGHER DOSAGES; CURING SPECTRA GROUP LIMITED, INC. 2002-08-13 US disclosed
US-6309797-B1 CONTAINING OXIDIZER; EXPOSURE TO ACTINIC RADIATION SPECTRA GROUP LIMITED, INC. 2001-10-30 US disclosed
US-6166013-A Glucocortiocoid-selective agents ABBOTT LABORATORIES (US) 2000-12-26 US disclosed