Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 5/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349699 | 0.91 | MEN1 (0.52) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL10350160 | 0.85 | HSD11B1 (0.44) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL10350159 | 0.83 | MEN1 (0.45) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL10349531 | 0.78 | MEN1 (0.48) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL23780405 | 0.76 | MEN1 (0.49) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL10049047 | 0.75 | KMT2A (0.67) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL10350179 | 0.74 | HSD11B1 (0.45) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL6438953 | 0.71 | MEN1 (0.76) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL23484310 | 0.71 | MEN1 (0.76) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL10017449 | 0.71 | MEN1 (0.63) | MEN1KMT2AHSD11B1ACLYACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166542-B1 | TRITERPENYL ESTERS OF ORGANIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND HYPOLIPIDEMIC AGENTS COMPOSED OF THEM | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1990-08-08 | — | — | EP | claimed |